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立克次氏體2點(diǎn)IgG免疫熒光玻片試劑盒
Rickettsia 2-Antigen MIF IgG kit
廣州健侖生物科技有限公司
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立克次氏體2點(diǎn)IgG免疫熒光玻片試劑盒
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【公司名稱】 廣州健侖生物科技有限公司
【】 楊永漢
【】
【騰訊 】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-3室
【企業(yè)文化】
這項(xiàng)研究發(fā)表于《PLoS ONE》雜志上,Kumar,以及合著者、MU獸醫(yī)醫(yī)學(xué)院的副教授杰弗里·布萊恩,使用稱為ODDHSL的細(xì)菌通訊分子用來(lái)治療在培養(yǎng)基中生長(zhǎng)的人胰腺癌細(xì)胞。經(jīng)過(guò)治療后,人胰腺癌細(xì)胞停止繁殖,未能遷移并開(kāi)始死亡。
“我們之所以使用胰腺癌細(xì)胞,是因?yàn)檫@些細(xì)胞是發(fā)生在人體內(nèi)zui強(qiáng)大的,侵襲性的以及難以殺滅的癌細(xì)胞,” Kumar說(shuō)。“為了表明,這種分子不僅可以阻止癌細(xì)胞擴(kuò)散,而且實(shí)際上也會(huì)導(dǎo)致它們死亡,這是非常令人興奮的。因?yàn)檫@個(gè)治療方法表明,其很有希望應(yīng)用于像胰腺癌這種侵襲性的癌癥。我們相信它也可用于其他類型的癌細(xì)胞,以及我們實(shí)驗(yàn)室正在其他類型的癌細(xì)胞中測(cè)試該治療方法。”
Kumar說(shuō),他研究的下一步是在動(dòng)物和人體試驗(yàn)發(fā)生前,尋找一個(gè)更有效的方式將該分子引入癌細(xì)胞中。
“現(xiàn)在,我們zui大的挑戰(zhàn)是,尋找一種有效的方式引入該分子,” Kumar說(shuō)。“在這個(gè)時(shí)候,我們只能夠用這種分子在實(shí)驗(yàn)室中治療癌細(xì)胞?,F(xiàn)在,我們使用一個(gè)更好的方法來(lái)處理動(dòng)物癌癥,看看這個(gè)治療是否真的有效。本研究的早期結(jié)果是有希望的。如果進(jìn)一步的研究,包括動(dòng)物實(shí)驗(yàn),都成功后,下一步是將這個(gè)方法應(yīng)用于臨床試驗(yàn)。”
The study, published in PLoS ONE, by Kumar and co-author Jeffrey Bryan, an associate professor at MU Veterinary Medical School, uses a bacterial communication molecule called ODDHSL to treat human pancreas that grows in culture cancer cell. After treatment, human pancreatic cancer cells stop multiplying, fail to migrate and begin to die.
"The reason we use pancreatic cancer is because these cells are the most powerful, aggressive and hard-to-kill cancer in the body," Kumar said. "It's very exciting to show that this molecule not only stops the spread of cancer cells but actually causes them to die, as this treatment shows promise for promising invasiveness like pancreatic cancer We believe it is also available for other types of cancer cells and our laboratory is testing the treatment in other types of cancer cells. "
Kumar said the next step in his research is to find a more effective way to introduce the molecule into cancer cells before animal and human trials occur.
"Now, our biggest challenge is to find an effective way to introduce that molecule," Kumar said. "At this point, we were only able to use this molecule to treat cancer cells in the laboratory, and now we use a better approach to treating animal cancers and see if the treatment is really effective. The early results of this study were Hopefully, if further research, including animal experiments, is successful, the next step is to apply the method to clinical trials. "