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甲型流感病毒核酸檢測(cè)試劑盒(PCR方法)
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甲型流感病毒核酸檢測(cè)試劑盒(PCR方法)
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研究人員驚訝的是,寒冷引起的米色脂肪補(bǔ)充幾乎*依賴于免疫系統(tǒng)。這違反了既定的理論,即營(yíng)養(yǎng)和能量代謝在很大程度上被認(rèn)為是大腦和內(nèi)分泌系統(tǒng)控制的,Chawla說,在確定了調(diào)控米色脂肪發(fā)展的細(xì)胞和分子途徑后,現(xiàn)在就可以針對(duì)任何其組件來刺激熱量消耗和治療肥胖。
陽光等外部條件觸發(fā)的細(xì)胞信號(hào)傳導(dǎo),允許生物適應(yīng)當(dāng)前的環(huán)境條件。在需要做出應(yīng)答的時(shí)候,機(jī)體會(huì)激活一系列的化學(xué)信號(hào)。通常這種信號(hào)一開始是很強(qiáng)的,一段時(shí)間之后會(huì)受到限制,信號(hào)減弱甚至*被關(guān)閉。這樣的限制機(jī)制是非常關(guān)鍵的,但迄今未知人們對(duì)它們的了解還很有限,科學(xué)家們大多更關(guān)注一開始的激活過程。
現(xiàn)在,加州大學(xué)伯克利分校和卡內(nèi)基科學(xué)研究所的研究人員對(duì)擬南芥進(jìn)行了研究,他們發(fā)現(xiàn)這種植物可以通過特定機(jī)制減弱外部信號(hào)的強(qiáng)度,擬南芥是一種常用的模式生物。這項(xiàng)研究發(fā)表在六月六日的science雜志上。
研究顯示,擬南芥幼苗從黑暗環(huán)境轉(zhuǎn)到陽光下時(shí),會(huì)引發(fā)一個(gè)“快速而廣泛”的基因表達(dá)重置,進(jìn)而長(zhǎng)成我們常見的綠色幼苗。這一過程需要一個(gè)限制性的機(jī)制,幫助細(xì)胞重新穩(wěn)定以達(dá)到新的平衡。研究人員發(fā)現(xiàn),這種機(jī)制位于細(xì)胞核中,而且與加速機(jī)制直接相連。
The researchers were surprised that cold-induced beige fat supplementation relied almost exclusively on the immune system. This runs counter to the established theory that nutrition and energy metabolism are largely thought to be under the control of the brain and endocrine system, Chawla said after identifying the cellular and molecular pathways that regulate the development of beige fat, Components to stimulate calories and treat obesity.
Sunshine and other external conditions trigger cell signaling, allowing the organism to adapt to current environmental conditions. When needed to respond, the body activates a series of chemical signals. Usually this kind of signal is very strong from the beginning, after a period of time will be limited, the signal is weakened or even compley shut down. Such a restriction mechanism is crucial, but so far it is unknown that people have limited understanding of them and most scientists are more concerned with the initial activation process.
Researchers at the University of California, Berkeley, and the Carnegie Institution of Science, have studied Arabidopsis and found that this plant can attenuate the intensity of external signals through specific mechanisms. Arabidopsis is a commonly used model organism. The study was published in the June 6 science magazine.
Research shows that when the Arabidopsis seedlings are switched from the dark to the sun, they trigger a "rapid and widespread" reset of gene expression, which in turn leads to our common green seedlings. This process requires a restrictive mechanism to help cells re-stabilize to reach a new equilibrium. The researchers found that this mechanism is located in the nucleus and is directly linked to the acceleration mechanism.