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乙型流感IgM ELISA抗原免疫層析法檢測試紙
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乙型流感IgM ELISA抗原免疫層析法檢測試紙
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【公司名稱】 廣州健侖生物科技有限公司
【市場部】 楊永漢
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【騰訊 】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室
目前,人類對短期進(jìn)入微重力環(huán)境適應(yīng)過程中的有關(guān)生物學(xué)機(jī)制有些初步了解,長期(數(shù)年)在空間生活的影響還有待進(jìn)一步認(rèn)識。細(xì)胞是構(gòu)成生命有機(jī)體的基本結(jié)構(gòu)和功能的單位,不管在失重條件下人體在生理等方面表現(xiàn)如何,微重力環(huán)境下產(chǎn)生的所有效應(yīng)均是單細(xì)胞本身或細(xì)胞間相互產(chǎn)生反應(yīng)的zui高形式。有名的細(xì)胞生物學(xué)家B.Wilson早在1925年就指出,生命科學(xué)問題的答案必定從細(xì)胞中去尋找。開展空問細(xì)胞科學(xué)研究是人類認(rèn)識及征服太空的必由之路。但是細(xì)胞的生長需要一定的條件,包括溫度、濕度、氧氣、養(yǎng)料、pH等,它們有復(fù)雜的代謝需要,并且對器皿壁的相互作用和流體應(yīng)力十分敏感,尤其對纖弱的哺乳動物細(xì)胞更是如此,因而空間細(xì)胞培養(yǎng)的研究是開展空間細(xì)胞生物學(xué)研究的基礎(chǔ)與前提條件。
近年來,生物醫(yī)學(xué)界報道了許多成功的臨床應(yīng)用例子,如單克隆抗體、基因工程重組蛋白、細(xì)胞因子、疫苗等,這些生物技術(shù)產(chǎn)品都有很高的經(jīng)濟(jì)和社會效益,往往涉及動、植物細(xì)胞的大規(guī)模培養(yǎng)技術(shù)。微重力環(huán)境為細(xì)胞培養(yǎng)提供許多有利之處,由于空間無沉降無對流的特性,物質(zhì)可以均勻懸浮,細(xì)胞不會因重力場的影響而沉降堆積在一個表面,這對于進(jìn)行細(xì)胞的高密度培養(yǎng),提高介質(zhì)的利用率和單位容積的產(chǎn)量,減少其它蛋白的污染都是有利的;并且空間純凈的培養(yǎng)環(huán)境,獲得更加均一、更加純凈的物質(zhì)的潛力,防止污染等,為空問制藥帶來了許多有利之處;特別是近些年來報道空間細(xì)胞的生物合成和分泌作用發(fā)生改變,某些重要蛋白質(zhì)的產(chǎn)量和品質(zhì)可以提高;在微重力下細(xì)胞具有三維生長的潛能。因而空間細(xì)胞培養(yǎng)是目前看好的三大空間生物技術(shù)(蛋白質(zhì)結(jié)晶,細(xì)胞培養(yǎng),生物分離)之一,也是空間生物加工的重要組成部分。國外在空間細(xì)胞培養(yǎng)方面所用的裝置在70年代初期一般都是由小的培養(yǎng)容器組成,但是細(xì)胞的生長需要一定的條件,包括溫度、濕度、氧氣、養(yǎng)料、pH等,它們有復(fù)雜的代謝需要,并且對器皿壁的相互作用和流體應(yīng)力十分敏感,尤其對纖弱的哺乳動物細(xì)胞更是如此,因而空間細(xì)胞培養(yǎng)的研究是開展空間細(xì)胞生物學(xué)研究的基礎(chǔ)與前提條件。
At present, human beings have some initial understanding about the biological mechanism in the adaptation process of short-term access to the micro-gravity environment. The impact of long-term (years) living in space needs to be further recognized. Cells constitute the basic structure and function of living organisms. Regardless of their physiology under conditions of weightlessness, all the effects produced under the micro-gravity environment are the highest forms of single cell or cell-cell interactions. Famous cell biologist As early as 1925, Wilson pointed out that the answer to the life sciences problem must be sought from the cell. It is the only way for human beings to understand and conquer space in order to carry out scientific research in space-based cells. However, the growth of cells requires certain conditions, including temperature, humidity, oxygen, nutrients, pH, etc., which have complex metabolic requirements and are very sensitive to vessel wall interactions and fluid stress, especially to delicate mammalian cells Thus, the study of space cell culture is the basis and prerequisite for the study of space cell biology.
In recent years, the biomedical community reported many successful clinical application examples, such as monoclonal antibodies, recombinant proteins, cytokines, vaccines, these biotechnology products have high economic and social benefits, often involving animals and plants Large-scale cell culture technology. Microgravity environment for cell culture provides many advantages, due to space-free non-convective convection, the material can be uniformly suspended, the cell will not be deposited due to the influence of the gravitational field accumulation in a surface, which for high-density cell culture, It is advantageous to increase the utilization rate of the medium and the yield per unit volume, and to reduce the pollution of other proteins; and the space-pure culture environment, the potential of obtaining a more homogeneous and pure substance, prevention of pollution and the like, Many advantages. Especially in recent years, it has been reported that the biosynthesis and secretion of space cells have changed, the yield and quality of some important proteins can be improved, and the cells have the potential of three-dimensional growth under microgravity. Therefore, the space cell culture is one of the three major space biotechnology (protein crystallization, cell culture and biological separation) currently favored by the world and is also an important part of the biological processing of space. In the early 1970s, the devices used in the overseas cell culture generally consisted of small culture vessels, but cell growth required certain conditions including temperature, humidity, oxygen, nutrients, pH, etc., which required complex metabolic needs , And is very sensitive to the vessel wall interaction and fluid stress, especially to the delicate mammalian cells. Therefore, the research of space cell culture is the basis and precondition for the research of space cell biology.